Familias Unidas is a family-centered drug use and sexual risk behavior prevention intervention for Hispanic youth and their families. Familias Unidas was specifically developed for Hispanics. It helps empower parents to speak with their adolescents about how to prevent drug use and sexual risk behaviors. Familias Unidas is a multilevel intervention that targets risk (e.g., poor adolescent communication) and protective factors (e.g., parental involvement) at the family, peer, and, school level. Familias Unidas has been adapted for use on the Internet and is currently being tested for obesity prevention, and delivery in primary care settings.